Spears will guest-star on the planned installment of the music-themed show in which the cast sings only Spears's songs.
"Britney, I think 100 percent, is going to be on the episode" for a "couple of scenes," Murphy said Tuesday during a radio appearance for "On-Air with Ryan Seacrest."
"The Britney episode, I'm here to say, is so reverential about her," Murphy added. "It's about her music and it's not about her personal life."
watch her: